๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ๏ผๆฌ็ฏ๏ผ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ
Intralymphatic histiocytosis
Intralymphatic histiocytosis
Clinical features Intralymphatic histiocytosis (IH) (intravascular lymphangitis, intravascular histiocytosis) is a rare disorder with relatively few cases described in the literature so far.1โ11 It is more common in middle aged to elderly females with predilection for the upper and lower limbs and less commonly the face. Almost half of the cases associated with rheumatoid arthritis present in the vicinity of joints affected by the disease.2โ4,6,11 The appearance varies from ill-defined plaques to a pattern mimicking livedo reticularis. In some patients there is association with another form of chronic inflammation, whilst in others there no apparent associated disease.11 A role for chronic inflammation is supported by reports of IH arising in postoperative scars following insertion of metallic joint prosthesis and following mastectomy in breast cancer, as well as cases occurring in association with colonic cancer, tonsillitis, and vulval ulceration.5โ10 Response to therapy is poor, and persistence tends to be the rule.
Hemophagocytic lymphohistiocytosis