๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ๏ผๆฌ็ฏ๏ผ
็พ็ ๅฎ็พฉ่ๅ้ก
- Naegeli-Franceschetti-Jadassohn syndrome ็บไธ็จฎๆฅต็บ็ฝ่ฆ็ๅค่ๅฑค็ผ่ฒไธ่ฏ (ectodermal dysplasia) ไน้บๅณ่ฎ็ฐๅ๏ผๅ้ซๆ่ฒ้ซ้กฏๆง้บๅณ (autosomal dominant)ใ
่จๅบ็นๅพต (Clinical Features)
- ็นๅพต็บ้ ธ้จใ่ปๅนน่ๅ่ข็็ฎ่็ถฒ็ๆ็็ๅๆ้ง็่ฒ็ด ๆฒ่ (reticulate patchy and mottled hyperpigmentation)ใ
- ็ผบไน็ฎ็ด (absence of dermatoglyphics)ใ
- ็ฐๆผซๆงๅ/ๆ้ป็ๆ่น ่งๅ็ (diffuse and/or punctate palmoplantar keratoderma)ใ
- ๆ็ฒ็้คไธ่ฏ (nail dystrophy)ใ็้ฝ็ฐๅธธ (teeth abnormalities)ใ
- ๆฑ่ บๅๆณไธ่ถณ (hypohidrosis) ๅฐ่ด่็ฑไธ่ฏ (heat intolerance)ใ
็ ็จ
- ็ถฒ็่ฒ็ด ๆฒ่ๅพๅๆผ้ ธ้จๅจๅ่ผๆ้กฏ๏ผ้ๆฅๆๅพ้ๆผธๆถ้๏ผๆผ่ๅนดๅฏ่ฝๅฎๅ จๆถๅคฑใ
- ็้ฝไพต็ฏ้ๅธธๅด้๏ผๅฏ่ฝๆผ็ๅฝๆฉๆๅณๅฎๅ จ่ซ่ฝใ
ๅ 20-33๏ผNaegeli-Franceschetti-Jadassohn syndrome๏ผๅธธ่ฆๆ่น ่งๅ็ (palmoplantar keratoderma)ใ