๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ๏ผๆฌ็ฏ๏ผ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ
Dermal hyperneury
Dermal hyperneury
Clinical features Dermal hyperneury is a well-recognized phenomenon which can be localized or multifocal.1โ7 When localized, it is usually associated with a trauma (including chronic scratching). It may be seen as an incidental finding in association with other cutaneous lesions or rarely in biopsies from notalgia paresthetica.1โ3 The multifocal form is generally considered syndromic; association with multiple endocrine neoplasia type IIB/MEN2B (RET at 10q11.21), Cowden syndrome (PTEN at 10q23.31), and neurofibromatosis type 2 (NF2 at 22q12.2) have been documented (see also mucosal neuromas), and it is very rare.4โ6 However, a subset of multifocal lesions are idiopathic and not associated with syndromes.
Fig. 35.298 Morton neuroma: the nerve trunk is markedly distorted by intense concentric fibrosis.