๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ๏ผๆฌ็ฏ๏ผ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ
Spindled cells
Spindled cells
The spindled cell variant is characterized by cells with elongated, narrow, tapering, cytoplasmic processes, which in nonpigmented variants may be confused with cells of mesenchymal derivation and therefore misdiagnosed as a variety of soft tissue neoplasms.
Occasional melanomas are exceedingly pleomorphic, containing tumor giant cells with enlarged nucleoli and conspicuous, frequently abnormal, mitotic figures; these variants must sometimes be distinguished from
1320 Melanoma
metastatic tumors, including pleomorphic secondary carcinoma, sarcomas, and even anaplastic CD30+ anaplastic large cell lymphoma (Figs 26.40โ26.42).
Fig. 26.40 Giant cell melanoma: within the dermis is a deposit of metastatic melanoma.