๐Ÿ—‚ ็ธฝ็›ฎ้Œ„ ๏ฝœ ๐Ÿ“– ่‹ฑๆ–‡ๅŽŸๆ–‡๏ผˆๆœฌ็ฏ‡๏ผ‰ ๏ฝœ ๐Ÿ“ ๅฎŒๆ•ด็ฟป่ญฏ ๏ฝœ โญ ็ฒพ่ฏ็ญ†่จ˜

Compound blue nevus

Compound blue nevus

Clinical features Compound blue nevus (superficial blue nevus with prominent intraepidermal dendritic melanocytes) is a rarely documented variant of blue nevus that presents as blue-gray to blue or black papules or nodules measuring from 2 to 4โ€ฏmm in greatest dimension.1โ€“3 Compound blue nevus shows predilection for the trunk, followed by extremities and head and neck area.1โ€“3 The lesion shows female predominance.

Histologic features Histologically, the compound blue nevus is a symmetrical, well-delineated, and dome-shaped proliferation combining the features of a common blue nevus with epidermal hyperpigmentation and an intraepidermal dendritic cell population (Fig. 25.232).1 Junctional nesting is usually absent.

Fig. 25.232 Compound blue nevus: in addition to a dermal component, dendritic cells are apparent in the epidermis.

Fig. 25.233 Hypopigmented blue nevus: residual pigmentation is seen on the left side of the field. On the right, there is a paucicellular sclerosing component.