๐Ÿ—‚ ็ธฝ็›ฎ้Œ„ ๏ฝœ ๐Ÿ“– ่‹ฑๆ–‡ๅŽŸๆ–‡๏ผˆๆœฌ็ฏ‡๏ผ‰ ๏ฝœ ๐Ÿ“ ๅฎŒๆ•ด็ฟป่ญฏ ๏ฝœ โญ ็ฒพ่ฏ็ญ†่จ˜

Follicular ichthyosis

Follicular ichthyosis

Follicular ichthyosis (ichthyosis follicularis) is an umbrella term or histologic pattern that is present in many conditions and is defined by follicular orthohyperkeratosis with or without hypergranulosis in the infundibulum.1 For differential diagnosis see Table 3.3.

76 Disorders of keratinization

A

A

B

B

Fig. 3.56 Conradi-Hรผnermann-Happle syndrome: (A) there is hyperkeratosis, acanthosis, and a reduced granular cell layer. Note the basophilic deposits within the thickened stratum corneum; (B) the basophilic deposits represent calcium as seen in this von Kossa preparation.

Table 3.3 Histologic patterns of ichthyotic skin disorders