疾病定義與分類
- 此疾病又稱為 idiopathic lenticular mucocutaneous pigmentation（特發性透鏡狀皮膚黏膜色素沉著），於色素沉著疾患 (disorders of pigmentation) 章節中討論。
圖 25-5：Laugier-Hunziker 症候群 (Laugier-Hunziker syndrome)：指甲出現縱向色素帶 (longitudinal pigmented bands)。由 S.-B. Woo, MD, Harvard Medical School, Boston, USA 提供。
Fig. 25.5 Laugier-Hunziker syndrome: longitudinal pigmented bands in the nails. By courtesy of S.-B. Woo, MD, Harvard Medical School, Boston, USA.
圖 25-6：單純性雀斑樣痣 (lentigo simplex)：可見棘層肥厚 (acanthosis) 並伴隨表皮突 (epidermal ridges) 延長。基底層內的黑色素細胞 (melanocytes) 數目增加。表皮有過度色素沉著 (excessive pigmentation)，但無交界活性 (junctional activity)。
Fig. 25.6 Lentigo simplex: there is acanthosis with elongation of the epidermal ridges. Basally located melanocytes are increased in number. There is excessive pigmentation of the epidermis, but no junctional activity is present.
圖 25-7：單純性雀斑樣痣 (lentigo simplex)：近觀視野顯示黑色素細胞 (melanocytes) 數目增加。
Fig. 25.7 Lentigo simplex: close-up view showing increased numbers of melanocytes.
圖 25-8：單純性雀斑樣痣 (lentigo simplex)：注意巨黑色素小體 (macromelanosomes) 的存在。
Fig. 25.8 Lentigo simplex: note the presence of macromelanosomes.