๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ๏ผๆฌ็ฏ๏ผ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ
Unilesional mycosis fungoides
Unilesional mycosis fungoides
Clinical features Unilesional (solitary) MF is very rare. Patients usually develop a solitary, slowly growing patch or plaque, typically on the trunk or upper extremity.1โ9 Although most documented cases have been in adults, there are occasional instances of childhood presentation.3,10 Folliculotropic and hypopigmented variants have been reported.3,4 Although complete remission is generally achieved following treatment (e.g., with excision, localized electron beam therapy or topical nitrogen mustard), occasional recurrences have been noted and noncontiguous spread may occur after many years.5,6 Systemic spread and death have not been described, reflecting the excellent prognosis of early-stage disease.
Histologic features Histologically, unilesional MF is indistinguishable from the more usual multilesional variant. Clonal TCR gene rearrangements are present in up to 50% of cases.