๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ๏ผๆฌ็ฏ๏ผ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ
Epithelioid cells
Epithelioid cells
Epithelioid melanoma cells are large and rounded with abundant, often eosinophilic, cytoplasm and contain prominent pleomorphic vesicular nuclei with conspicuous eosinophilic nucleoli. Mitotic figures may be either scant or numerous and sometimes abnormal. Pigmentation is variable and can be abundant or minimal. When minimal, Masson-Fontana silver staining is useful to reveal small quantities of pigment not detectable with conventional hematoxylin and eosin stained sections. Alternatively, immunohistochemistry may be necessary to establish the diagnosis (Fig. 26.39).
Fig. 26-39 (caption embedded in image / ๅ่ชช็็ๆผๅๅ ง)