๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ๏ผๆฌ็ฏ๏ผ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ
Ink spot lentigo
Ink spot lentigo
Clinical features Ink spot lentigo (reticulated black solar lentigo, reticular lentigo, acquired reticulated lentigo, reticulated melanotic macule) is a rare variant of lentigo; it is particularly important because clinically it may be confused with melanoma. It affects fair-skinned individuals with red to blond hair and blue
Histologic features Ink spot lentigo shows lentiginous hyperplasia with very marked basal cell hyperpigmentation, rete-tip accentuation, and characteristic achromic skip areas (Fig. 25.16).1โ3 Melanocytes may be normal or slightly increased in number, but there is no cytological atypia or junctional activity. Pigmentary incontinence is usually evident, and a perivascular chronic inflammatory cell infiltrate is commonly present.

Fig. 25.16 Ink spot lentigo: there is massive basal cell hyperpigmentation.