๐Ÿ—‚ ็ธฝ็›ฎ้Œ„ ๏ฝœ ๐Ÿ“– ่‹ฑๆ–‡ๅŽŸๆ–‡๏ผˆๆœฌ็ฏ‡๏ผ‰ ๏ฝœ ๐Ÿ“ ๅฎŒๆ•ด็ฟป่ญฏ ๏ฝœ โญ ็ฒพ่ฏ็ญ†่จ˜

Ink spot lentigo

Ink spot lentigo

Clinical features Ink spot lentigo (reticulated black solar lentigo, reticular lentigo, acquired reticulated lentigo, reticulated melanotic macule) is a rare variant of lentigo; it is particularly important because clinically it may be confused with melanoma. It affects fair-skinned individuals with red to blond hair and blue

Histologic features Ink spot lentigo shows lentiginous hyperplasia with very marked basal cell hyperpigmentation, rete-tip accentuation, and characteristic achromic skip areas (Fig. 25.16).1โ€“3 Melanocytes may be normal or slightly increased in number, but there is no cytological atypia or junctional activity. Pigmentary incontinence is usually evident, and a perivascular chronic inflammatory cell infiltrate is commonly present.

Fig. 25.16 Ink spot lentigo: there is massive basal cell hyperpigmentation.