๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ๏ผๆฌ็ฏ๏ผ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ
Calcinosis cutis
Calcinosis cutis
Calcinosis cutis may occur when connective tissue is abnormal (dystrophic) or where calcium or phosphate levels in the blood are high (metastatic); alternatively, there may be no obvious underlying cause (idiopathic) (Table 13.5).1โ3
608 Degenerative and metabolic diseases
Type Distribution Clinical features
Dystrophic Localized Widespread
Acne scars; fat cell necrosis; epidermoid cysts; pilomatrixoma; infantile calcinosis of the heel Dermatomyositis; systemic lupus erythematosus; Ehlers-Danlos syndrome; pseudoxanthoma elasticum
Metastatic Hypercalcemic Hyperparathyroidism; sarcoidosis; vitamin D excess; milk alkali syndrome; destructive bone disease Normocalcemic Chronic renal failure; pseudohypoparathyroidism
Idiopathic Generalized Localized
Calcinosis universalis Subepidermal calcified nodule; localized idiopathic dermal calcinosis; tumoral; scrotal
Table 13.5 Classification of calcinosis cutis