๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ๏ผๆฌ็ฏ๏ผ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ
Zoon vulvitis (plasma cell vulvitis)
Zoon vulvitis (plasma cell vulvitis)
This variant of Zoon is the female counterpart of the more common Zoon balanitis and was also described by Zoon after it had been noted by Garnier.1
491 Inflammatory dermatoses
Histologic features The histology is the same as that described for ZB. In one histologic study, the percentage of plasma cells seen was felt to be the most important parameter in making the diagnosis.8 However, the site of the biopsy is important as there are increased numbers of plasma cells seen in the vestibule normally, and this should not be misinterpreted. An exceptional case of Zoon vulvitis with prominent mucinous metaplasia has been described.9
Fig. 12.64 Zoon balanitis: note the epidermal thinning, spongiosis, and a dense superficial inflammatory cell infiltrate.
Fig. 12.66 Zoon vulvitis (plasma cell vulvitis): purpuric change at vestibule.