๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ๏ผๆฌ็ฏ๏ผ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ
Paraneoplastic pemphigus
Paraneoplastic pemphigus
Erythema multiforme-like histologic features are an integral feature of paraneoplastic pemphigus (see Chapter 5).
typical poikiloderma presents in a photodistribution, predominantly affecting the sides of the face and neck and the โVโ of the chest (Fig. 7.98).1โ4 Middle-aged and elderly women, menopausal females, are predominantly affected. Possible etiological factors include hormonal effects, phototoxicity, or photoallergy possibly due to perfumes or fragrances.4โ8 Familial cases have been documented.4
Fig. 7.97 Poikiloderma: close-up view.
Fig. 7.98 Poikiloderma of Civatte: note the mottled hyperpigmentation in a characteristic distribution. By courtesy of the Institute of Dermatology, London, UK.